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Colorectal carcinomas in MUTYH-associated polyposis display histopathological similarities to microsatellite unstable carcinomas

BACKGROUND: MUTYH-associated polyposis (MAP) is a recessively inherited disorder which predisposes biallelic carriers for a high risk of polyposis and colorectal carcinoma (CRC). Since about one third of the biallelic MAP patients in population based CRC series has no adenomas, this study aimed to i...

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Detalles Bibliográficos
Autores principales: Nielsen, Maartje, de Miranda, Noel FCC, van Puijenbroek, Marjo, Jordanova, Ekaterina S, Middeldorp, Anneke, van Wezel, Tom, van Eijk, Ronald, Tops, Carli MJ, Vasen, Hans FA, Hes, Frederik J, Morreau, Hans
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2706846/
https://www.ncbi.nlm.nih.gov/pubmed/19527492
http://dx.doi.org/10.1186/1471-2407-9-184