Cytogenetic mapping of 25 goat mammary gland Expressed Sequence Tags (ESTs)

Today, there is a shift towards a positional candidate approach in the molecular identification of genes. This study reports on an Expressed Sequence Tags (ESTs) mapping initiative in goats, based on sequence information gathered from a previous mammary gland cDNA systematic sequencing project. A to...

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Detalles Bibliográficos
Autores principales: Le Provost, Fabienne, Schibler, Laurent, Oustry-Vaiman, Anne, Martin, Patrice, Cribiu, Edmond P
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2000
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2706890/
https://www.ncbi.nlm.nih.gov/pubmed/14736395
http://dx.doi.org/10.1186/1297-9686-32-3-311
Descripción
Sumario:Today, there is a shift towards a positional candidate approach in the molecular identification of genes. This study reports on an Expressed Sequence Tags (ESTs) mapping initiative in goats, based on sequence information gathered from a previous mammary gland cDNA systematic sequencing project. A total of 25 novel genes was localised cytogenetically on 16 goat chromosomes. Six of these ESTs were found to map to cattle milk QTL regions. These results made it possible to assess the use of ESTs as a shortcut to the molecular identification of some QTLs and as a valuable tool for comparative mapping.

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