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Dissecting Structural and Functional Diversity of the Lantibiotic Mersacidin
Mersacidin is a tetracyclic lantibiotic with antibacterial activity against Gram-positive pathogens. To probe the specificity of the biosynthetic pathway of mersacidin and obtain analogs with improved antibacterial activity, an efficient system for generating variants of this lantibiotic was develop...
| Autores principales: | , , , , , , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2009
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2706954/ https://www.ncbi.nlm.nih.gov/pubmed/19477413 http://dx.doi.org/10.1016/j.chembiol.2009.03.011 |