Dissecting Structural and Functional Diversity of the Lantibiotic Mersacidin

Mersacidin is a tetracyclic lantibiotic with antibacterial activity against Gram-positive pathogens. To probe the specificity of the biosynthetic pathway of mersacidin and obtain analogs with improved antibacterial activity, an efficient system for generating variants of this lantibiotic was develop...

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Detalles Bibliográficos
Autores principales: Appleyard, Antony N., Choi, Shaila, Read, Daniel M., Lightfoot, Ann, Boakes, Steven, Hoffmann, Anja, Chopra, Ian, Bierbaum, Gabriele, Rudd, Brian A.M., Dawson, Michael J., Cortes, Jesus
Formato: Texto
Lenguaje:English
Publicado: Elsevier 2009
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2706954/
https://www.ncbi.nlm.nih.gov/pubmed/19477413
http://dx.doi.org/10.1016/j.chembiol.2009.03.011

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