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How good is the macaque monkey model of the human brain?
Macaque monkeys are widely used in order to understand the mechanisms of the human brain. But humans have capacities not found in monkeys, and their brains differ in important ways, for example in the proportions of different regions and in microstructure. However, this does not mean that we must ab...
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Formato: | Texto |
Lenguaje: | English |
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Current Biology
2009
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2706975/ https://www.ncbi.nlm.nih.gov/pubmed/19261463 http://dx.doi.org/10.1016/j.conb.2009.01.002 |
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author | Passingham, Richard |
author_facet | Passingham, Richard |
author_sort | Passingham, Richard |
collection | PubMed |
description | Macaque monkeys are widely used in order to understand the mechanisms of the human brain. But humans have capacities not found in monkeys, and their brains differ in important ways, for example in the proportions of different regions and in microstructure. However, this does not mean that we must abandon the monkey model, only that wherever possible, we should test whether generalizations can be made. One strategy is to use fMRI to visualize activations in humans, and compare these with activations in monkeys. Where the results are the same, we can then use information from single unit recording in those areas to suggest the mechanisms by which those areas perform their functions in the human brain. |
format | Text |
id | pubmed-2706975 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2009 |
publisher | Current Biology |
record_format | MEDLINE/PubMed |
spelling | pubmed-27069752009-07-10 How good is the macaque monkey model of the human brain? Passingham, Richard Curr Opin Neurobiol Article Macaque monkeys are widely used in order to understand the mechanisms of the human brain. But humans have capacities not found in monkeys, and their brains differ in important ways, for example in the proportions of different regions and in microstructure. However, this does not mean that we must abandon the monkey model, only that wherever possible, we should test whether generalizations can be made. One strategy is to use fMRI to visualize activations in humans, and compare these with activations in monkeys. Where the results are the same, we can then use information from single unit recording in those areas to suggest the mechanisms by which those areas perform their functions in the human brain. Current Biology 2009-02 /pmc/articles/PMC2706975/ /pubmed/19261463 http://dx.doi.org/10.1016/j.conb.2009.01.002 Text en © 2009 Elsevier Ltd. https://creativecommons.org/licenses/by/3.0/ Open Access under CC BY 3.0 (https://creativecommons.org/licenses/by/3.0/) license |
spellingShingle | Article Passingham, Richard How good is the macaque monkey model of the human brain? |
title | How good is the macaque monkey model of the human brain? |
title_full | How good is the macaque monkey model of the human brain? |
title_fullStr | How good is the macaque monkey model of the human brain? |
title_full_unstemmed | How good is the macaque monkey model of the human brain? |
title_short | How good is the macaque monkey model of the human brain? |
title_sort | how good is the macaque monkey model of the human brain? |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2706975/ https://www.ncbi.nlm.nih.gov/pubmed/19261463 http://dx.doi.org/10.1016/j.conb.2009.01.002 |
work_keys_str_mv | AT passinghamrichard howgoodisthemacaquemonkeymodelofthehumanbrain |