Cargando…

Akt Phosphorylates Both Tsc1 and Tsc2 in Drosophila, but Neither Phosphorylation Is Required for Normal Animal Growth

Akt, an essential component of the insulin pathway, is a potent inducer of tissue growth. One of Akt's phosphorylation targets is Tsc2, an inhibitor of the anabolic kinase TOR. This could account for part of Akt's growth promoting activity. Although phosphorylation of Tsc2 by Akt does occu...

Descripción completa

Detalles Bibliográficos
Autores principales: Schleich, Sibylle, Teleman, Aurelio A.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2706976/
https://www.ncbi.nlm.nih.gov/pubmed/19609361
http://dx.doi.org/10.1371/journal.pone.0006305

Ejemplares similares