Lys169 of Human Glucokinase Is a Determinant for Glucose Phosphorylation: Implication for the Atomic Mechanism of Glucokinase Catalysis

Glucokinase (GK), a glucose sensor, maintains plasma glucose homeostasis via phosphorylation of glucose and is a potential therapeutic target for treating maturity-onset diabetes of the young (MODY) and persistent hyperinsulinemic hypoglycemia of infancy (PHHI). To characterize the catalytic mechani...

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Detalles Bibliográficos
Autores principales: Zhang, Jian, Li, Chenjing, Shi, Ting, Chen, Kaixian, Shen, Xu, Jiang, Hualiang
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2706991/
https://www.ncbi.nlm.nih.gov/pubmed/19617908
http://dx.doi.org/10.1371/journal.pone.0006304

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2706991/
https://www.ncbi.nlm.nih.gov/pubmed/19617908
http://dx.doi.org/10.1371/journal.pone.0006304

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