Inactivation of TIF1γ Cooperates with Kras(G12D) to Induce Cystic Tumors of the Pancreas

Inactivation of the Transforming Growth Factor Beta (TGFβ) tumor suppressor pathway contributes to the progression of Pancreatic Ductal AdenoCarcinoma (PDAC) since it is inactivated in virtually all cases of this malignancy. Genetic lesions inactivating this pathway contribute to pancreatic tumor pr...

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Detalles Bibliográficos
Autores principales: Vincent, David F., Yan, Kai-Ping, Treilleux, Isabelle, Gay, Fabien, Arfi, Vanessa, Kaniewsky, Bastien, Marie, Julien C., Lepinasse, Florian, Martel, Sylvie, Goddard-Leon, Sophie, Iovanna, Juan L., Dubus, Pierre, Garcia, Stéphane, Puisieux, Alain, Rimokh, Ruth, Bardeesy, Nabeel, Scoazec, Jean-Yves, Losson, Régine, Bartholin, Laurent
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2706992/
https://www.ncbi.nlm.nih.gov/pubmed/19629168
http://dx.doi.org/10.1371/journal.pgen.1000575

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2706992/
https://www.ncbi.nlm.nih.gov/pubmed/19629168
http://dx.doi.org/10.1371/journal.pgen.1000575

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