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Deoxyamphimedine, a Pyridoacridine Alkaloid, Damages DNA via the Production of Reactive Oxygen Species

Marine pyridoacridines are a class of aromatic chemicals that share an 11H-pyrido[4,3,2-mn]acridine skeleton. Pyridoacridine alkaloids display diverse biological activities including cytotoxicity, fungicidal and bactericidal properties, production of reactive oxygen species (ROS) and topoisomerase i...

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Detalles Bibliográficos
Autores principales: Marshall, Kathryn M., Andjelic, Cynthia D., Tasdemir, Deniz, Concepción, Gisela P., Ireland, Chris M., Barrows, Louis R.
Formato: Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2707043/
https://www.ncbi.nlm.nih.gov/pubmed/19597581
http://dx.doi.org/10.3390/md7020196