New Azaphilones, Seco-Chaetomugilins A and D, Produced by a Marine-Fish-Derived Chaetomium globosum

Seco-chaetomugilins A and D were isolated from a strain of Chaetomium globosum that was originally isolated from the marine fish Mugil cephalus, and their absolute stereostructures were elucidated on the basis of spectroscopic analyses, including 1D and 2D NMR techniques, along with the chemical tra...

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Autores principales: Yamada, Takeshi, Muroga, Yasuhide, Tanaka, Reiko
Formato: Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International 2009
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2707045/
https://www.ncbi.nlm.nih.gov/pubmed/19597583
http://dx.doi.org/10.3390/md7020249
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author Yamada, Takeshi
Muroga, Yasuhide
Tanaka, Reiko
author_facet Yamada, Takeshi
Muroga, Yasuhide
Tanaka, Reiko
author_sort Yamada, Takeshi
collection PubMed
description Seco-chaetomugilins A and D were isolated from a strain of Chaetomium globosum that was originally isolated from the marine fish Mugil cephalus, and their absolute stereostructures were elucidated on the basis of spectroscopic analyses, including 1D and 2D NMR techniques, along with the chemical transformation from known chaetomugilins A and D. Seco-chaetomugilin D exhibited growth inhibitory activity against cultured P388, HL-60, L1210, and KB cells.
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spelling pubmed-27070452009-07-08 New Azaphilones, Seco-Chaetomugilins A and D, Produced by a Marine-Fish-Derived Chaetomium globosum Yamada, Takeshi Muroga, Yasuhide Tanaka, Reiko Mar Drugs Article Seco-chaetomugilins A and D were isolated from a strain of Chaetomium globosum that was originally isolated from the marine fish Mugil cephalus, and their absolute stereostructures were elucidated on the basis of spectroscopic analyses, including 1D and 2D NMR techniques, along with the chemical transformation from known chaetomugilins A and D. Seco-chaetomugilin D exhibited growth inhibitory activity against cultured P388, HL-60, L1210, and KB cells. Molecular Diversity Preservation International 2009-06-16 /pmc/articles/PMC2707045/ /pubmed/19597583 http://dx.doi.org/10.3390/md7020249 Text en © 2009 by the authors; licensee Molecular Diversity Preservation International, Basel, Switzerland. http://creativecommons.org/licenses/by/3.0 This article is an open-access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).
spellingShingle Article
Yamada, Takeshi
Muroga, Yasuhide
Tanaka, Reiko
New Azaphilones, Seco-Chaetomugilins A and D, Produced by a Marine-Fish-Derived Chaetomium globosum
title New Azaphilones, Seco-Chaetomugilins A and D, Produced by a Marine-Fish-Derived Chaetomium globosum
title_full New Azaphilones, Seco-Chaetomugilins A and D, Produced by a Marine-Fish-Derived Chaetomium globosum
title_fullStr New Azaphilones, Seco-Chaetomugilins A and D, Produced by a Marine-Fish-Derived Chaetomium globosum
title_full_unstemmed New Azaphilones, Seco-Chaetomugilins A and D, Produced by a Marine-Fish-Derived Chaetomium globosum
title_short New Azaphilones, Seco-Chaetomugilins A and D, Produced by a Marine-Fish-Derived Chaetomium globosum
title_sort new azaphilones, seco-chaetomugilins a and d, produced by a marine-fish-derived chaetomium globosum
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2707045/
https://www.ncbi.nlm.nih.gov/pubmed/19597583
http://dx.doi.org/10.3390/md7020249
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AT murogayasuhide newazaphilonessecochaetomugilinsaanddproducedbyamarinefishderivedchaetomiumglobosum
AT tanakareiko newazaphilonessecochaetomugilinsaanddproducedbyamarinefishderivedchaetomiumglobosum

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