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Nanomechanical In Situ Monitoring of Proteolysis of Peptide by Cathepsin B
Characterization and control of proteolysis of peptides by specific cellular protease is a priori requisite for effective drug discovery. Here, we report the nanomechanical, in situ monitoring of proteolysis of peptide chain attributed to protease (Cathepsin B) by using a resonant nanomechanical mic...
| Autores principales: | , , , , , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2009
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2707113/ https://www.ncbi.nlm.nih.gov/pubmed/19606222 http://dx.doi.org/10.1371/journal.pone.0006248 |