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Functional impact of endotoxin receptor CD14 polymorphisms on transcriptional activity

The polymorphism rs2569190 within the CD14 endotoxin (lipopolysaccharide, LPS) receptor gene is associated with various disease conditions that are assumed to rely on endotoxin sensitivity. In vitro experiments suggest that the T allele sensitizes the host for exogenous or endogenous LPS via an enha...

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Detalles Bibliográficos
Autores principales:	Mertens, Jasmin, Bregadze, Rusudan, Mansur, Ashham, Askar, Eva, Bickeböller, Heike, Ramadori, Giuliano, Mihm, Sabine
Formato:	Texto
Lenguaje:	English
Publicado:	Springer-Verlag 2009
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2707953/ https://www.ncbi.nlm.nih.gov/pubmed/19468702 http://dx.doi.org/10.1007/s00109-009-0479-7

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