Protein Never in Mitosis Gene A Interacting-1 regulates calpain activity and the degradation of cyclooxygenase-2 in endothelial cells

BACKGROUND: The peptidyl-proline isomerase, Protein Never in Mitosis Gene A Interacting-1 (PIN1), regulates turnover of inducible nitric oxide synthase (iNOS) in murine aortic endothelial cells (MAEC) stimulated with E. coli endotoxin (LPS) and interferon-γ (IFN). Degradation of iNOS was reduced by...

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Detalles Bibliográficos
Autores principales: Liu, Tongzheng, Schneider, Ryan A, Shah, Vaibhav, Huang, Yongcheng, Likhotvorik, Rostislav I, Keshvara, Lakhu, Hoyt, Dale G
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2708161/
https://www.ncbi.nlm.nih.gov/pubmed/19545424
http://dx.doi.org/10.1186/1476-9255-6-20

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