249 TP53 mutation has high prevalence and is correlated with larger and poorly differentiated HCC in Brazilian patients

BACKGROUND: Ser-249 TP53 mutation (249(Ser)) is a molecular evidence for aflatoxin-related carcinogenesis in Hepatocellular Carcinoma (HCC) and it is frequent in some African and Asian regions, but it is unusual in Western countries. HBV has been claimed to add a synergic effect on genesis of this p...

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Detalles Bibliográficos
Autores principales: Nogueira, Jeronimo A, Ono-Nita, Suzane K, Nita, Marcelo E, de Souza, Marcelo MT, do Carmo, Eliane P, Mello, Evandro S, Scapulatempo, Cristovan, Paranaguá-Vezozzo, Denise C, Carrilho, Flair J, Alves, Venancio AF
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2708192/
https://www.ncbi.nlm.nih.gov/pubmed/19558663
http://dx.doi.org/10.1186/1471-2407-9-204

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