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CXCR4 expression on circulating pan-cytokeratin positive cells is associated with survival in patients with advanced non-small cell lung cancer
BACKGROUND: The CXC chemokine, CXCL12, and its receptor, CXCR4 promote metastases of a variety of solid tumors, including non-small cell lung cancer (NSCLC). The expression of CXCR4 on tumor cells may represent a critical biomarker for their propensity to metastasize. This study was performed to eva...
Autores principales: | Reckamp, Karen L, Figlin, Robert A, Burdick, Marie D, Dubinett, Steven M, Elashoff, Robert M, Strieter, Robert M |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2708193/ https://www.ncbi.nlm.nih.gov/pubmed/19563666 http://dx.doi.org/10.1186/1471-2407-9-213 |
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