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Heterogeneous Nuclear Ribonucleoprotein L Is a Subunit of Human KMT3a/Set2 Complex Required for H3 Lys-36 Trimethylation Activity in Vivo

The presence of histone H3 lysine 36 methylation (H3K36me) correlates with actively transcribed genes. In yeast, histone H3K36me mediated by KMT3 (also known as Set2) recruits a histone deacetylase complex, Rpd3s, to ensure the fidelity of transcription initiation. We report the purification of huma...

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Detalles Bibliográficos
Autores principales: Yuan, Wen, Xie, Jingwei, Long, Chengzu, Erdjument-Bromage, Hediye, Ding, Xiaojun, Zheng, Yong, Tempst, Paul, Chen, She, Zhu, Bing, Reinberg, Danny
Formato: Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2708867/
https://www.ncbi.nlm.nih.gov/pubmed/19332550
http://dx.doi.org/10.1074/jbc.M808431200