Membrane Bound Monomer of Staphylococcal α-Hemolysin Induces Caspase Activation and Apoptotic Cell Death despite Initiation of Membrane Repair Pathway

BACKGROUND: Wild type Staphylococcal α-hemolysin (α-HL) assembly on target mammalian cells usually results in necrotic form of cell death; however, caspase activation also occurs. The pathways of caspase activation due to binding/partial assembly by α-HL are unknown till date. RESULTS: Cells treated...

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Detalles Bibliográficos
Autores principales: Srivastava, Saumya S., Pany, Satyabrata, Sneh, Amita, Ahmed, Neesar, Rahman, Aejazur, Musti, Krishnasastry V.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2708924/
https://www.ncbi.nlm.nih.gov/pubmed/19621082
http://dx.doi.org/10.1371/journal.pone.0006293

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