Administration of the fixed combination of latanoprost 0.005% and timolol 0.5% in glaucoma patients with an intraocular pressure over 30 mmHg

PURPOSE: To evaluate the intraocular pressure (IOP) reducing effect of a fixed combination of 0.005% latanoprost and 0.5% timolol in patients with an IOP of 30 mmHg or higher. DESIGN: Prospective, randomized clinical trial. PARTICIPANTS: Twenty-eight patients. METHODS: Patients had received no prior...

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Detalles Bibliográficos
Autores principales: Özkurt, Yelda Buyru, Sengor, Tomris, Evciman, Tufan, Haboğlu, Melih, Baş, Gökçen, Aydın, Sevda
Formato: Texto
Lenguaje:English
Publicado: Dove Medical Press 2009
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2708984/
https://www.ncbi.nlm.nih.gov/pubmed/19668587
Descripción
Sumario:PURPOSE: To evaluate the intraocular pressure (IOP) reducing effect of a fixed combination of 0.005% latanoprost and 0.5% timolol in patients with an IOP of 30 mmHg or higher. DESIGN: Prospective, randomized clinical trial. PARTICIPANTS: Twenty-eight patients. METHODS: Patients had received no prior medical glaucoma treatment. Routine ophthalmic examinations and visual field tests were performed before and after treatment for each patient. RESULTS: Mean IOP was 32.28 ± 0.92 mmHg before treatment. Mean IOP levels were 18.75 ± 0.68 for the first day, 17.96 ± 0.90 for the first week and 17.64 ± 0.66 for the first month after treatment. CONCLUSION: A fixed combination of latanoprost 0.005% and timolol 0.5% is effective in significantly reducing IOP in glaucoma patients with an IOP greater than 30 mmHg.

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