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Differential effects of interleukin-1β and S100B on amyloid precursor protein in rat retinal neurons

PURPOSE: Interleukin-1β (IL-1β) and S100B calcium binding protein B (S100B) have been implicated in the pathogenesis of Alzheimer’s disease. Both are present in and around senile plaques and have been shown to increase levels of amyloid precursor protein (APP) mRNA in vitro. However, it is not known...

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Detalles Bibliográficos
Autores principales: Anderson, Peter JB, Watts, Helena R, Jen, Sheila, Gentleman, Stephen M, Moncaster, Juliet A, Walsh, D T, Jen, Ling-Sun
Formato: Texto
Lenguaje:English
Publicado: Dove Medical Press 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2708995/
https://www.ncbi.nlm.nih.gov/pubmed/19668572

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