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Age-related macular degeneration: current treatments

PURPOSE: Although important progress has been made in understanding age-related macular degeneration (AMD), management of the disease continues to be a challenge. AMD research has led to a widening of available treatment options and improved prognostic perspectives. This essay reviews these treatmen...

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Autores principales: Hubschman, Jean Pierre, Reddy, Shantan, Schwartz, Steven D
Formato: Texto
Lenguaje:English
Publicado: Dove Medical Press 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2709020/
https://www.ncbi.nlm.nih.gov/pubmed/19668560
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author Hubschman, Jean Pierre
Reddy, Shantan
Schwartz, Steven D
author_facet Hubschman, Jean Pierre
Reddy, Shantan
Schwartz, Steven D
author_sort Hubschman, Jean Pierre
collection PubMed
description PURPOSE: Although important progress has been made in understanding age-related macular degeneration (AMD), management of the disease continues to be a challenge. AMD research has led to a widening of available treatment options and improved prognostic perspectives. This essay reviews these treatment options. DESIGN: Interpretative essay. METHODS: Literature review and interpretation. RESULTS: Current treatments to preserve vision in patients with non-exudative AMD include antioxidant vitamins and mineral supplementations. Exudative AMD is currently most often treated monthly with anti-VEGF intravitreal injections. However, investigators are beginning to experiment with combination therapy and surgical approaches in an attempt to limit the number of treatment and reduce the financial burden on the health care system. CONCLUSION: By better understanding the basis and pathogenesis of AMD, newer therapies will continue to be developed that target specific pathways in patients with AMD, with the hoped for outcome of better management of the disease and improved visual acuity.
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spelling pubmed-27090202009-08-10 Age-related macular degeneration: current treatments Hubschman, Jean Pierre Reddy, Shantan Schwartz, Steven D Clin Ophthalmol Review PURPOSE: Although important progress has been made in understanding age-related macular degeneration (AMD), management of the disease continues to be a challenge. AMD research has led to a widening of available treatment options and improved prognostic perspectives. This essay reviews these treatment options. DESIGN: Interpretative essay. METHODS: Literature review and interpretation. RESULTS: Current treatments to preserve vision in patients with non-exudative AMD include antioxidant vitamins and mineral supplementations. Exudative AMD is currently most often treated monthly with anti-VEGF intravitreal injections. However, investigators are beginning to experiment with combination therapy and surgical approaches in an attempt to limit the number of treatment and reduce the financial burden on the health care system. CONCLUSION: By better understanding the basis and pathogenesis of AMD, newer therapies will continue to be developed that target specific pathways in patients with AMD, with the hoped for outcome of better management of the disease and improved visual acuity. Dove Medical Press 2009 2009-06-02 /pmc/articles/PMC2709020/ /pubmed/19668560 Text en © 2009 Hubschman et al, publisher and licensee Dove Medical Press Ltd. This is an Open Access article which permits unrestricted noncommercial use, provided the original work is properly cited.
spellingShingle Review
Hubschman, Jean Pierre
Reddy, Shantan
Schwartz, Steven D
Age-related macular degeneration: current treatments
title Age-related macular degeneration: current treatments
title_full Age-related macular degeneration: current treatments
title_fullStr Age-related macular degeneration: current treatments
title_full_unstemmed Age-related macular degeneration: current treatments
title_short Age-related macular degeneration: current treatments
title_sort age-related macular degeneration: current treatments
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2709020/
https://www.ncbi.nlm.nih.gov/pubmed/19668560
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