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Neurodegeneration in Alzheimer's disease: caspases and synaptic element interdependence
Extensive genetic, biochemical, and histological evidence has implicated the amyloid-β peptide (Aβ) in Alzheimer's disease pathogenesis, and several mechanisms have been suggested, such as metal binding, reactive oxygen species production, and membrane pore formation. However, recent evidence a...
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| Formato: | Texto |
| Lenguaje: | English |
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BioMed Central
2009
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2709109/ https://www.ncbi.nlm.nih.gov/pubmed/19558683 http://dx.doi.org/10.1186/1750-1326-4-27 |