Cargando…

Heteroarotinoids with Anti-Cancer Activity Against Ovarian Cancer Cells

The Flex-Het compound 10a (SHetA2-NSC 721689) {[4-nitrophenylamino][(2,2,4,4-tetramethylthiochroman-6-yl)amino]methane-1-thione]} has shown promise in preclinical testing as an anti-cancer agent without evidence of toxicity, skin irritancy, or teratogenicity. One objective of this study was to synth...

Descripción completa

Detalles Bibliográficos
Autores principales:	Le, Thanh C., Berlin, K. Darrell, Benson, Stacy D., Eastman, Margaret A., Bell-Eunice, Gianna, Nelson, Anna C., Benbrook, Doris M.
Formato:	Texto
Lenguaje:	English
Publicado:	Bentham Science Publishers Ltd. 2007
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2709466/ https://www.ncbi.nlm.nih.gov/pubmed/19662136 http://dx.doi.org/10.2174/1874104500701010011

Ejemplares similares

Flexible heteroarotinoid (Flex-Het) SHetA2 inhibits angiogenesis in vitro and in vivo
por: Myers, Tashanna, et al.
Publicado: (2008)

Pharmacokinetics and interspecies scaling of a novel, orally-bioavailable anti-cancer drug, SHetA2
por: Sharma, Ankur, et al.
Publicado: (2018)

SHetA2 interference with mortalin binding to p66shc and p53 identified using drug-conjugated magnetic microspheres
por: Benbrook, Doris Mangiaracina, et al.
Publicado: (2013)

SHetA2 Attack on Mortalin and Colleagues in Cancer Therapy and Prevention
por: Benbrook, Doris Mangiaracina
Publicado: (2022)

Targeting autophagy in cancer management – strategies and developments
por: Ozpolat, Bulent, et al.
Publicado: (2015)

Utility and Mechanism of SHetA2 and Paclitaxel for Treatment of Endometrial Cancer
por: Chandra, Vishal, et al.
Publicado: (2021)

Dataset on mucin 1 and 4 proteins and SialyT and T antigens staining patterns in cervical cancer primary tumors and metastatic lymph nodes
por: Rai, Rajani, et al.
Publicado: (2023)

Histopathologic, Genetic and Molecular Characterization of Endometrial Cancer Racial Disparity
por: Javadian, Pouya, et al.
Publicado: (2021)

Preclinical Efficacy and Involvement of AKT, mTOR, and ERK Kinases in the Mechanism of Sulforaphane against Endometrial Cancer
por: Rai, Rajani, et al.
Publicado: (2020)

Sera Protein Signatures of Endometrial Cancer Lymph Node Metastases
por: Benbrook, Doris Mangiaracina, et al.
Publicado: (2022)

Patient-Derived Xenografts of High-Grade Serous Ovarian Cancer Subtype as a Powerful Tool in Pre-Clinical Research
por: Cybula, Magdalena, et al.
Publicado: (2021)

Modeling effects of diabetes and obesity co-morbidities in endometrial cancer development and progression
por: Benbrook, Doris, et al.
Publicado: (2012)

Identification of Candidate Biomarker and Drug Targets for Improving Endometrial Cancer Racial Disparities
por: Javadian, Pouya, et al.
Publicado: (2022)

Similarities and Differences of Hsp70, hsc70, Grp78 and Mortalin as Cancer Biomarkers and Drug Targets
por: Rai, Rajani, et al.
Publicado: (2021)

Distinct mechanism of cervical cancer cell death caused by the investigational new drug SHetA2
por: Rai, Rajani, et al.
Publicado: (2022)

Ruxolitinib synergistically enhances the anti-tumor activity of paclitaxel in human ovarian cancer
por: Han, Ernest S., et al.
Publicado: (2018)

Synergistic Anti-Tumor Activity by Targeting Multiple Signaling Pathways in Ovarian Cancer
por: Wen, Wei, et al.
Publicado: (2020)

Anti-angiogenic therapy for ovarian cancer
por: García García, Yolanda, et al.
Publicado: (2020)

Aberrant NRP-1 expression serves as predicator of metastatic endometrial and lung cancers
por: Okon, Imoh S., et al.
Publicado: (2015)

The anti-cancer effects of itraconazole in epithelial ovarian cancer
por: Choi, Chel Hun, et al.
Publicado: (2017)

Bioanalytical method development and validation of HPLCUV assay for the quantification of SHetA2 in mouse and human plasma: Application to pharmacokinetics study
por: Sharma, Ankur, et al.
Publicado: (2017)

Curcumin induces chemo/radio-sensitization in ovarian cancer cells and curcumin nanoparticles inhibit ovarian cancer cell growth
por: Yallapu, Murali M, et al.
Publicado: (2010)

Targeted anti-vascular therapies for ovarian cancer: current evidence
por: Hall, M, et al.
Publicado: (2013)

Complementary Targeting of Rb Phosphorylation and Growth in Cervical Cancer Cell Cultures and a Xenograft Mouse Model by SHetA2 and Palbociclib
por: Kennedy, Amy L., et al.
Publicado: (2020)

Silencing BMI1 radiosensitizes human breast cancer cells by inducing DNA damage and autophagy
por: Griffith, James, et al.
Publicado: (2017)

Anti-Müllerian hormone as a marker of ovarian reserve and premature ovarian insufficiency in children and women with cancer: a systematic review
por: Anderson, Richard A, et al.
Publicado: (2022)

Allogeneic human neural stem cells for improved therapeutic delivery to peritoneal ovarian cancer
por: Mooney, Rachael, et al.
Publicado: (2021)

Anti-Tumor and Anti-Invasive Effects of ONC201 on Ovarian Cancer Cells and a Transgenic Mouse Model of Serous Ovarian Cancer
por: Fan, Yali, et al.
Publicado: (2022)

Anti-cancer and Sensibilisation Effect of Triptolide on Human Epithelial Ovarian Cancer
por: Hu, Hui, et al.
Publicado: (2016)

Ivermectin Augments the Anti-Cancer Activity of Pitavastatin in Ovarian Cancer Cells
por: Jawad, Mohammed Jasim, et al.
Publicado: (2023)

Anti-cancer effect of fenbendazole-incorporated PLGA nanoparticles in ovarian cancer
por: Chang, Chi-Son, et al.
Publicado: (2023)

Claudin-4 localization in epithelial ovarian cancer
por: Neville, Margaret C., et al.
Publicado: (2022)

Synergistic Lethality of Mifepristone and LY294002 in Ovarian Cancer Cells
por: Wempe, Stacy L., et al.
Publicado: (2013)

Anti-CDCP1 immuno-conjugates for detection and inhibition of ovarian cancer
por: Harrington, Brittney S., et al.
Publicado: (2020)

The Dawning of the Age of Personalized Medicine in Gynecologic Oncology
por: Leslie, Kimberly K., et al.
Publicado: (2020)

Asparagus officinalis Exhibits Anti-Tumorigenic and Anti-Metastatic Effects in Ovarian Cancer
por: Xu, Guangxu, et al.
Publicado: (2021)

Ovarian cancer
por: Kerbrat, P, et al.
Publicado: (2001)

Anti-cancer effects of Kaempferia parviflora on ovarian cancer SKOV3 cells
por: Paramee, Suthasinee, et al.
Publicado: (2018)

Complementary anti-cancer pathways triggered by inhibition of sideroflexin 4 in ovarian cancer
por: Tesfay, Lia, et al.
Publicado: (2022)

Enhancements Needed in GE Crop and Food Regulation in the U.S.
por: Benbrook, Charles
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_jnl50ktv1ki5ci1uk05oishtp1