Molecular Docking and Analysis of Survivin Delta-Ex3 Isoform Protein

This project explores molecular models of Survivin Delta-Ex3, H-Ras, and their binding sites, and generates energy optimized 3D coordinates of docked poses and conformations of the XY2 ligand molecule in the active site of Delta-Ex3. The aim is to propose an effective anti-cancer drug that induces a...

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Detalles Bibliográficos
Autor principal: Ezziane, Z
Formato: Texto
Lenguaje:English
Publicado: Bentham Science Publishers Ltd 2008
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2709477/
https://www.ncbi.nlm.nih.gov/pubmed/19662140
http://dx.doi.org/10.2174/1874104500802010016
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author Ezziane, Z
author_facet Ezziane, Z
author_sort Ezziane, Z
collection PubMed
description This project explores molecular models of Survivin Delta-Ex3, H-Ras, and their binding sites, and generates energy optimized 3D coordinates of docked poses and conformations of the XY2 ligand molecule in the active site of Delta-Ex3. The aim is to propose an effective anti-cancer drug that induces apoptosis and inhibits tumor angiogenesis.
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spelling pubmed-27094772009-08-06 Molecular Docking and Analysis of Survivin Delta-Ex3 Isoform Protein Ezziane, Z Open Med Chem J Article This project explores molecular models of Survivin Delta-Ex3, H-Ras, and their binding sites, and generates energy optimized 3D coordinates of docked poses and conformations of the XY2 ligand molecule in the active site of Delta-Ex3. The aim is to propose an effective anti-cancer drug that induces apoptosis and inhibits tumor angiogenesis. Bentham Science Publishers Ltd 2008-03-27 /pmc/articles/PMC2709477/ /pubmed/19662140 http://dx.doi.org/10.2174/1874104500802010016 Text en 2008 Bentham Science Publishers Ltd http://creativecommons.org/licenses/by/2.5/ This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.5/) which permits unrestrictive use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Article
Ezziane, Z
Molecular Docking and Analysis of Survivin Delta-Ex3 Isoform Protein
title Molecular Docking and Analysis of Survivin Delta-Ex3 Isoform Protein
title_full Molecular Docking and Analysis of Survivin Delta-Ex3 Isoform Protein
title_fullStr Molecular Docking and Analysis of Survivin Delta-Ex3 Isoform Protein
title_full_unstemmed Molecular Docking and Analysis of Survivin Delta-Ex3 Isoform Protein
title_short Molecular Docking and Analysis of Survivin Delta-Ex3 Isoform Protein
title_sort molecular docking and analysis of survivin delta-ex3 isoform protein
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2709477/
https://www.ncbi.nlm.nih.gov/pubmed/19662140
http://dx.doi.org/10.2174/1874104500802010016
work_keys_str_mv AT ezzianez moleculardockingandanalysisofsurvivindeltaex3isoformprotein

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