The ATR-Chk1 pathway plays a role in the generation of centrosome aberrations induced by Rad51C dysfunction

Rad51C is a central component of two complexes formed by five Rad51 paralogs in vertebrates. These complexes are involved in repairing DNA double-strand breaks through homologous recombination. Despite accumulating evidence suggesting that the paralogs may prevent aneuploidy by controlling centrosom...

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Detalles Bibliográficos
Autores principales: Katsura, Mari, Tsuruga, Takanori, Date, Osamu, Yoshihara, Takashi, Ishida, Mari, Tomoda, Yoshitaka, Okajima, Miyuki, Takaku, Motoki, Kurumizaka, Hitoshi, Kinomura, Aiko, Mishima, Hiromu K., Miyagawa, Kiyoshi
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2009
Materias:
Genome Integrity, Repair and Replication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2709562/
https://www.ncbi.nlm.nih.gov/pubmed/19403737
http://dx.doi.org/10.1093/nar/gkp262

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