Analyzing the forces binding a restriction endonuclease to DNA using a synthetic nanopore

Restriction endonucleases are used prevalently in recombinant DNA technology because they bind so stably to a specific target sequence and, in the presence of cofactors, cleave double-helical DNA specifically at a target sequence at a high rate. Using synthetic nanopores along with molecular dynamic...

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Detalles Bibliográficos
Autores principales: Dorvel, B., Sigalov, G., Zhao, Q., Comer, J., Dimitrov, V., Mirsaidov, U., Aksimentiev, A., Timp, G.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2009
Materias:
Structural Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2709577/
https://www.ncbi.nlm.nih.gov/pubmed/19433506
http://dx.doi.org/10.1093/nar/gkp317

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2709577/
https://www.ncbi.nlm.nih.gov/pubmed/19433506
http://dx.doi.org/10.1093/nar/gkp317

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