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Analyzing the forces binding a restriction endonuclease to DNA using a synthetic nanopore
Restriction endonucleases are used prevalently in recombinant DNA technology because they bind so stably to a specific target sequence and, in the presence of cofactors, cleave double-helical DNA specifically at a target sequence at a high rate. Using synthetic nanopores along with molecular dynamic...
| Autores principales: | , , , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2009
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2709577/ https://www.ncbi.nlm.nih.gov/pubmed/19433506 http://dx.doi.org/10.1093/nar/gkp317 |