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Quantitative evaluation of DNA methylation by optimization of a differential-high resolution melt analysis protocol
DNA methylation is a key regulator of gene transcription. Alterations in DNA methylation patterns are common in most cancers, occur early in carcinogenesis and can be detected in body fluids. Reliable and sensitive quantitative assays are required to improve the diagnostic role of methylation in the...
Autores principales: | , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2709587/ https://www.ncbi.nlm.nih.gov/pubmed/19454604 http://dx.doi.org/10.1093/nar/gkp383 |