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In silico selection of RNA aptamers
In vitro selection of RNA aptamers that bind to a specific ligand usually begins with a random pool of RNA sequences. We propose a computational approach for designing a starting pool of RNA sequences for the selection of RNA aptamers for specific analyte binding. Our approach consists of three step...
Autores principales: | Chushak, Yaroslav, Stone, Morley O. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2709588/ https://www.ncbi.nlm.nih.gov/pubmed/19465396 http://dx.doi.org/10.1093/nar/gkp408 |
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