Accuracy of genome-wide imputation of untyped markers and impacts on statistical power for association studies

BACKGROUND: Although high-throughput genotyping arrays have made whole-genome association studies (WGAS) feasible, only a small proportion of SNPs in the human genome are actually surveyed in such studies. In addition, various SNP arrays assay different sets of SNPs, which leads to challenges in com...

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Detalles Bibliográficos
Autores principales: Hao, Ke, Chudin, Eugene, McElwee, Joshua, Schadt, Eric E
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2709633/
https://www.ncbi.nlm.nih.gov/pubmed/19531258
http://dx.doi.org/10.1186/1471-2156-10-27

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2709633/
https://www.ncbi.nlm.nih.gov/pubmed/19531258
http://dx.doi.org/10.1186/1471-2156-10-27

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