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Accuracy of genome-wide imputation of untyped markers and impacts on statistical power for association studies
BACKGROUND: Although high-throughput genotyping arrays have made whole-genome association studies (WGAS) feasible, only a small proportion of SNPs in the human genome are actually surveyed in such studies. In addition, various SNP arrays assay different sets of SNPs, which leads to challenges in com...
Autores principales: | Hao, Ke, Chudin, Eugene, McElwee, Joshua, Schadt, Eric E |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2709633/ https://www.ncbi.nlm.nih.gov/pubmed/19531258 http://dx.doi.org/10.1186/1471-2156-10-27 |
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