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Case report: Malignant teratoma of the uterine corpus
BACKGROUND: Teratomas are the commonest germ cell tumours and are most frequently found in the testes and ovary. Extragonadal teratomas are rare and mainly occur in midline structures. Uterine teratomas are extremely rare with only a few previous case reports, usually involving mature teratomas of t...
Autores principales: | , , , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
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BioMed Central
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2709639/ https://www.ncbi.nlm.nih.gov/pubmed/19538751 http://dx.doi.org/10.1186/1471-2407-9-195 |
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author | Newsom-Davis, Thomas Poulter, Daniel Gray, Rebecca Ameen, Mohammed Lindsay, Iain Papanikolaou, Kyriakos Butler-Manuel, Simon Christmas, Timothy Townsend, Peter Seckl, Michael |
author_facet | Newsom-Davis, Thomas Poulter, Daniel Gray, Rebecca Ameen, Mohammed Lindsay, Iain Papanikolaou, Kyriakos Butler-Manuel, Simon Christmas, Timothy Townsend, Peter Seckl, Michael |
author_sort | Newsom-Davis, Thomas |
collection | PubMed |
description | BACKGROUND: Teratomas are the commonest germ cell tumours and are most frequently found in the testes and ovary. Extragonadal teratomas are rare and mainly occur in midline structures. Uterine teratomas are extremely rare with only a few previous case reports, usually involving mature teratomas of the uterine cervix. CASE PRESENTATION: We report an 82-year-old lady presenting with post-menopausal bleeding. Initial investigations revealed a benign teratoma of the uterus which was removed. Her symptoms persisted and a recurrent, now malignant, teratoma of the uterine corpus was resected at hysterectomy. Six months after surgery she relapsed with para-aortic lymphadenopathy and was treated with a taxane, etoposide and cisplatin-containing chemotherapy regimen followed by retroperitoneal lymph node dissection. CONCLUSION: In this report we discuss the aetiology, diagnosis and management of uterine teratomas, and review previous case studies. |
format | Text |
id | pubmed-2709639 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2009 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-27096392009-07-14 Case report: Malignant teratoma of the uterine corpus Newsom-Davis, Thomas Poulter, Daniel Gray, Rebecca Ameen, Mohammed Lindsay, Iain Papanikolaou, Kyriakos Butler-Manuel, Simon Christmas, Timothy Townsend, Peter Seckl, Michael BMC Cancer Case Report BACKGROUND: Teratomas are the commonest germ cell tumours and are most frequently found in the testes and ovary. Extragonadal teratomas are rare and mainly occur in midline structures. Uterine teratomas are extremely rare with only a few previous case reports, usually involving mature teratomas of the uterine cervix. CASE PRESENTATION: We report an 82-year-old lady presenting with post-menopausal bleeding. Initial investigations revealed a benign teratoma of the uterus which was removed. Her symptoms persisted and a recurrent, now malignant, teratoma of the uterine corpus was resected at hysterectomy. Six months after surgery she relapsed with para-aortic lymphadenopathy and was treated with a taxane, etoposide and cisplatin-containing chemotherapy regimen followed by retroperitoneal lymph node dissection. CONCLUSION: In this report we discuss the aetiology, diagnosis and management of uterine teratomas, and review previous case studies. BioMed Central 2009-06-18 /pmc/articles/PMC2709639/ /pubmed/19538751 http://dx.doi.org/10.1186/1471-2407-9-195 Text en Copyright ©2009 Newsom-Davis et al; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Case Report Newsom-Davis, Thomas Poulter, Daniel Gray, Rebecca Ameen, Mohammed Lindsay, Iain Papanikolaou, Kyriakos Butler-Manuel, Simon Christmas, Timothy Townsend, Peter Seckl, Michael Case report: Malignant teratoma of the uterine corpus |
title | Case report: Malignant teratoma of the uterine corpus |
title_full | Case report: Malignant teratoma of the uterine corpus |
title_fullStr | Case report: Malignant teratoma of the uterine corpus |
title_full_unstemmed | Case report: Malignant teratoma of the uterine corpus |
title_short | Case report: Malignant teratoma of the uterine corpus |
title_sort | case report: malignant teratoma of the uterine corpus |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2709639/ https://www.ncbi.nlm.nih.gov/pubmed/19538751 http://dx.doi.org/10.1186/1471-2407-9-195 |
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