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Cytokine-dependent and–independent gene expression changes and cell cycle block revealed in Trypanosoma cruzi-infected host cells by comparative mRNA profiling

BACKGROUND: The requirements for growth and survival of the intracellular pathogen Trypanosoma cruzi within mammalian host cells are poorly understood. Transcriptional profiling of the host cell response to infection serves as a rapid read-out for perturbation of host physiology that, in part, refle...

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Detalles Bibliográficos
Autores principales: Costales, Jaime A, Daily, Johanna P, Burleigh, Barbara A
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2709661/
https://www.ncbi.nlm.nih.gov/pubmed/19480704
http://dx.doi.org/10.1186/1471-2164-10-252