Rosiglitazone Prevents High Glucose-Induced Vascular Endothelial Growth Factor and Collagen IV Expression in Cultured Mesangial Cells

Peroxisome proliferator-activated receptor (PPARγ), a ligand-dependent transcription factor, negatively modulates high glucose effects. We postulated that rosiglitazone (RSG), an activator of PPARγ prevents the upregulation of vascular endothelial growth factor (VEGF) and collagen IV by mesangial ce...

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Detalles Bibliográficos
Autores principales: Whiteside, Catharine, Wang, Hong, Xia, Ling, Munk, Snezana, Goldberg, Howard J., Fantus, I. George
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2709725/
https://www.ncbi.nlm.nih.gov/pubmed/19609456
http://dx.doi.org/10.1155/2009/910783

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