MicroRNA-Biogenesis and Pre-mRNA Splicing Crosstalk

MicroRNAs (miRNAs) are often hosted in introns of protein-coding genes. Given that the same transcriptional unit can potentially give rise to both miRNA and mRNA transcripts raises the intriguing question of the level of interaction between these processes. Recent studies from transcription, pre-mRN...

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Detalles Bibliográficos
Autores principales: Shomron, Noam, Levy, Carmit
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2009
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2709726/
https://www.ncbi.nlm.nih.gov/pubmed/19606257
http://dx.doi.org/10.1155/2009/594678
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author Shomron, Noam
Levy, Carmit
author_facet Shomron, Noam
Levy, Carmit
author_sort Shomron, Noam
collection PubMed
description MicroRNAs (miRNAs) are often hosted in introns of protein-coding genes. Given that the same transcriptional unit can potentially give rise to both miRNA and mRNA transcripts raises the intriguing question of the level of interaction between these processes. Recent studies from transcription, pre-mRNA splicing, and miRNA-processing perspectives have investigated these relationships and yielded interesting, yet somewhat controversial findings. Here we discuss major studies in the field.
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spelling pubmed-27097262009-07-15 MicroRNA-Biogenesis and Pre-mRNA Splicing Crosstalk Shomron, Noam Levy, Carmit J Biomed Biotechnol Review Article MicroRNAs (miRNAs) are often hosted in introns of protein-coding genes. Given that the same transcriptional unit can potentially give rise to both miRNA and mRNA transcripts raises the intriguing question of the level of interaction between these processes. Recent studies from transcription, pre-mRNA splicing, and miRNA-processing perspectives have investigated these relationships and yielded interesting, yet somewhat controversial findings. Here we discuss major studies in the field. Hindawi Publishing Corporation 2009 2009-07-06 /pmc/articles/PMC2709726/ /pubmed/19606257 http://dx.doi.org/10.1155/2009/594678 Text en Copyright © 2009 N. Shomron and C. Levy. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
Shomron, Noam
Levy, Carmit
MicroRNA-Biogenesis and Pre-mRNA Splicing Crosstalk
title MicroRNA-Biogenesis and Pre-mRNA Splicing Crosstalk
title_full MicroRNA-Biogenesis and Pre-mRNA Splicing Crosstalk
title_fullStr MicroRNA-Biogenesis and Pre-mRNA Splicing Crosstalk
title_full_unstemmed MicroRNA-Biogenesis and Pre-mRNA Splicing Crosstalk
title_short MicroRNA-Biogenesis and Pre-mRNA Splicing Crosstalk
title_sort microrna-biogenesis and pre-mrna splicing crosstalk
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2709726/
https://www.ncbi.nlm.nih.gov/pubmed/19606257
http://dx.doi.org/10.1155/2009/594678
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AT levycarmit micrornabiogenesisandpremrnasplicingcrosstalk

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