Co-existence of acute myeloid leukemia with multilineage dysplasia and Epstein-Barr virus-associated T-cell lymphoproliferative disorder in a patient with rheumatoid arthritis: a case report

Rheumatoid arthritis (RA) is an autoimmune disease mediated by inflammatory processes mainly at the joints. Recently, awareness of Epstein-Barr virus (EBV)-associated T-cell lymphoproliferative disorder (T-LPD) has been heightened for its association with methotraxate usage in RA patients. In the co...

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Autores principales: Tokuhira, Michihide, Hanzawa, Kyoko, Watanabe, Reiko, Sekiguchi, Yasunobu, Nemoto, Tomoe, Toyozumi, Yasuo, Tamaru, Jun-ichi, Itoyama, Shinji, Suzuki, Katsuya, Kameda, Hideto, Mori, Shigehisa, Kizaki, Masahiro
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2709901/
https://www.ncbi.nlm.nih.gov/pubmed/19566938
http://dx.doi.org/10.1186/1756-8722-2-27
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author Tokuhira, Michihide
Hanzawa, Kyoko
Watanabe, Reiko
Sekiguchi, Yasunobu
Nemoto, Tomoe
Toyozumi, Yasuo
Tamaru, Jun-ichi
Itoyama, Shinji
Suzuki, Katsuya
Kameda, Hideto
Mori, Shigehisa
Kizaki, Masahiro
author_facet Tokuhira, Michihide
Hanzawa, Kyoko
Watanabe, Reiko
Sekiguchi, Yasunobu
Nemoto, Tomoe
Toyozumi, Yasuo
Tamaru, Jun-ichi
Itoyama, Shinji
Suzuki, Katsuya
Kameda, Hideto
Mori, Shigehisa
Kizaki, Masahiro
author_sort Tokuhira, Michihide
collection PubMed
description Rheumatoid arthritis (RA) is an autoimmune disease mediated by inflammatory processes mainly at the joints. Recently, awareness of Epstein-Barr virus (EBV)-associated T-cell lymphoproliferative disorder (T-LPD) has been heightened for its association with methotraxate usage in RA patients. In the contrary, acute myeloid leukemia with multilineage dysplasia (AML-MLD) has never been documented to be present concomitantly with the above two conditions. In this report we present a case of an autopsy-proven co-existence of AML-MLD and EBV-associated T-LPD in a patient with RA.
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spelling pubmed-27099012009-07-14 Co-existence of acute myeloid leukemia with multilineage dysplasia and Epstein-Barr virus-associated T-cell lymphoproliferative disorder in a patient with rheumatoid arthritis: a case report Tokuhira, Michihide Hanzawa, Kyoko Watanabe, Reiko Sekiguchi, Yasunobu Nemoto, Tomoe Toyozumi, Yasuo Tamaru, Jun-ichi Itoyama, Shinji Suzuki, Katsuya Kameda, Hideto Mori, Shigehisa Kizaki, Masahiro J Hematol Oncol Case Report Rheumatoid arthritis (RA) is an autoimmune disease mediated by inflammatory processes mainly at the joints. Recently, awareness of Epstein-Barr virus (EBV)-associated T-cell lymphoproliferative disorder (T-LPD) has been heightened for its association with methotraxate usage in RA patients. In the contrary, acute myeloid leukemia with multilineage dysplasia (AML-MLD) has never been documented to be present concomitantly with the above two conditions. In this report we present a case of an autopsy-proven co-existence of AML-MLD and EBV-associated T-LPD in a patient with RA. BioMed Central 2009-06-30 /pmc/articles/PMC2709901/ /pubmed/19566938 http://dx.doi.org/10.1186/1756-8722-2-27 Text en Copyright © 2009 Tokuhira et al; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License ( (http://creativecommons.org/licenses/by/2.0) ), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Tokuhira, Michihide
Hanzawa, Kyoko
Watanabe, Reiko
Sekiguchi, Yasunobu
Nemoto, Tomoe
Toyozumi, Yasuo
Tamaru, Jun-ichi
Itoyama, Shinji
Suzuki, Katsuya
Kameda, Hideto
Mori, Shigehisa
Kizaki, Masahiro
Co-existence of acute myeloid leukemia with multilineage dysplasia and Epstein-Barr virus-associated T-cell lymphoproliferative disorder in a patient with rheumatoid arthritis: a case report
title Co-existence of acute myeloid leukemia with multilineage dysplasia and Epstein-Barr virus-associated T-cell lymphoproliferative disorder in a patient with rheumatoid arthritis: a case report
title_full Co-existence of acute myeloid leukemia with multilineage dysplasia and Epstein-Barr virus-associated T-cell lymphoproliferative disorder in a patient with rheumatoid arthritis: a case report
title_fullStr Co-existence of acute myeloid leukemia with multilineage dysplasia and Epstein-Barr virus-associated T-cell lymphoproliferative disorder in a patient with rheumatoid arthritis: a case report
title_full_unstemmed Co-existence of acute myeloid leukemia with multilineage dysplasia and Epstein-Barr virus-associated T-cell lymphoproliferative disorder in a patient with rheumatoid arthritis: a case report
title_short Co-existence of acute myeloid leukemia with multilineage dysplasia and Epstein-Barr virus-associated T-cell lymphoproliferative disorder in a patient with rheumatoid arthritis: a case report
title_sort co-existence of acute myeloid leukemia with multilineage dysplasia and epstein-barr virus-associated t-cell lymphoproliferative disorder in a patient with rheumatoid arthritis: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2709901/
https://www.ncbi.nlm.nih.gov/pubmed/19566938
http://dx.doi.org/10.1186/1756-8722-2-27
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