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Comparison of Common Carotid Artery Intima-Media Thickness Between Brazilian Euro-Descendants and Afro-Descendants with Atherosclerosis Risk Factors

OBJECTIVE: To compare common carotid intima-media thickness (IMT) between the two major Brazilian ethnic groups (those of African descent and those of European descent) among individuals with one or more risk factors for atherosclerotic disease. METHOD: Two hundred and six patients with one or more...

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Autores principales: Casella, Ivan Benaduce, Sotelo, Fabio José Bonafé, Yamazaki, Yumiko, Presti, Calógero, Vassoler, Alecxander, Melo, Henry Augusto Hoffmann
Formato: Texto
Lenguaje:English
Publicado: Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2710439/
https://www.ncbi.nlm.nih.gov/pubmed/19606242
http://dx.doi.org/10.1590/S1807-59322009000700009
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author Casella, Ivan Benaduce
Sotelo, Fabio José Bonafé
Yamazaki, Yumiko
Presti, Calógero
Vassoler, Alecxander
Melo, Henry Augusto Hoffmann
author_facet Casella, Ivan Benaduce
Sotelo, Fabio José Bonafé
Yamazaki, Yumiko
Presti, Calógero
Vassoler, Alecxander
Melo, Henry Augusto Hoffmann
author_sort Casella, Ivan Benaduce
collection PubMed
description OBJECTIVE: To compare common carotid intima-media thickness (IMT) between the two major Brazilian ethnic groups (those of African descent and those of European descent) among individuals with one or more risk factors for atherosclerotic disease. METHOD: Two hundred and six patients with one or more risk factors for atherosclerotic disease were evaluated in a cross-sectional study in which their clinical, ethnic and Demographic characteristics were collected. All patients underwent duplex ultrasound examination of their carotid vessels to obtain IMT measurements. RESULTS: One hundred and fifty-three patients (74.3%) had a carotid IMT greater than 1.0 mm at one or more point of measurement in at least one common carotid artery. There was a significant correlation between older age and mean carotid wall thickness (R=0.479 / P<0.01). Multivariate analysis identified male sex, arterial hypertension and older age as variables associated with increased IMT (P<0.05 for all variables). When IMT was compared between the two ethnic groups in this study, no significant differences were noted. Euro-descendants and Afro-descendants had similar IMT values, even when the groups were stratified by degree of IMT (normal vs. increased) and presence of stroke and/or transient ischemic attack (yes vs. no). CONCLUSIONS: The risk factors associated with increased common carotid artery IMT in Brazilian individuals are similar to those in previously described populations. No differences were observed between the two main Brazilian ethnic groups. Longitudinal studies are required for a better evaluation of the incidence, etiologic factors and evolution of carotid intimomedial thickening in this population.
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spelling pubmed-27104392009-07-15 Comparison of Common Carotid Artery Intima-Media Thickness Between Brazilian Euro-Descendants and Afro-Descendants with Atherosclerosis Risk Factors Casella, Ivan Benaduce Sotelo, Fabio José Bonafé Yamazaki, Yumiko Presti, Calógero Vassoler, Alecxander Melo, Henry Augusto Hoffmann Clinics (Sao Paulo) Clinical Sciences OBJECTIVE: To compare common carotid intima-media thickness (IMT) between the two major Brazilian ethnic groups (those of African descent and those of European descent) among individuals with one or more risk factors for atherosclerotic disease. METHOD: Two hundred and six patients with one or more risk factors for atherosclerotic disease were evaluated in a cross-sectional study in which their clinical, ethnic and Demographic characteristics were collected. All patients underwent duplex ultrasound examination of their carotid vessels to obtain IMT measurements. RESULTS: One hundred and fifty-three patients (74.3%) had a carotid IMT greater than 1.0 mm at one or more point of measurement in at least one common carotid artery. There was a significant correlation between older age and mean carotid wall thickness (R=0.479 / P<0.01). Multivariate analysis identified male sex, arterial hypertension and older age as variables associated with increased IMT (P<0.05 for all variables). When IMT was compared between the two ethnic groups in this study, no significant differences were noted. Euro-descendants and Afro-descendants had similar IMT values, even when the groups were stratified by degree of IMT (normal vs. increased) and presence of stroke and/or transient ischemic attack (yes vs. no). CONCLUSIONS: The risk factors associated with increased common carotid artery IMT in Brazilian individuals are similar to those in previously described populations. No differences were observed between the two main Brazilian ethnic groups. Longitudinal studies are required for a better evaluation of the incidence, etiologic factors and evolution of carotid intimomedial thickening in this population. Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo 2009-07 /pmc/articles/PMC2710439/ /pubmed/19606242 http://dx.doi.org/10.1590/S1807-59322009000700009 Text en Copyright © 2009 Hospital das Clínicas da FMUSP
spellingShingle Clinical Sciences
Casella, Ivan Benaduce
Sotelo, Fabio José Bonafé
Yamazaki, Yumiko
Presti, Calógero
Vassoler, Alecxander
Melo, Henry Augusto Hoffmann
Comparison of Common Carotid Artery Intima-Media Thickness Between Brazilian Euro-Descendants and Afro-Descendants with Atherosclerosis Risk Factors
title Comparison of Common Carotid Artery Intima-Media Thickness Between Brazilian Euro-Descendants and Afro-Descendants with Atherosclerosis Risk Factors
title_full Comparison of Common Carotid Artery Intima-Media Thickness Between Brazilian Euro-Descendants and Afro-Descendants with Atherosclerosis Risk Factors
title_fullStr Comparison of Common Carotid Artery Intima-Media Thickness Between Brazilian Euro-Descendants and Afro-Descendants with Atherosclerosis Risk Factors
title_full_unstemmed Comparison of Common Carotid Artery Intima-Media Thickness Between Brazilian Euro-Descendants and Afro-Descendants with Atherosclerosis Risk Factors
title_short Comparison of Common Carotid Artery Intima-Media Thickness Between Brazilian Euro-Descendants and Afro-Descendants with Atherosclerosis Risk Factors
title_sort comparison of common carotid artery intima-media thickness between brazilian euro-descendants and afro-descendants with atherosclerosis risk factors
topic Clinical Sciences
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2710439/
https://www.ncbi.nlm.nih.gov/pubmed/19606242
http://dx.doi.org/10.1590/S1807-59322009000700009
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