Cargando…
TLR2-Dependent Inhibition of Macrophage Responses to IFN-γ Is Mediated by Distinct, Gene-Specific Mechanisms
Mycobacterium tuberculosis uses multiple mechanisms to avoid elimination by the immune system. We have previously shown that M. tuberculosis can inhibit selected macrophage responses to IFN-γ through TLR2-dependent and -independent mechanisms. To specifically address the role of TLR2 signaling in me...
Autores principales: | Benson, Sarah A., Ernst, Joel D. |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2009
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2710511/ https://www.ncbi.nlm.nih.gov/pubmed/19629181 http://dx.doi.org/10.1371/journal.pone.0006329 |
Ejemplares similares
-
Extracellular nicotinamide phosphoribosyltransferase boosts IFNγ-induced macrophage polarization independently of TLR4
por: Colombo, Giorgia, et al.
Publicado: (2022) -
Identification of the Molecular Mechanism by which TLR Ligation and IFN-γ Synergize to Induce Mig
por: Powell, Jonathan D., et al.
Publicado: (2004) -
IFN-γ selectively suppresses a subset of TLR4-activated genes and enhancers to potentiate macrophage activation
por: Kang, Kyuho, et al.
Publicado: (2019) -
TLR7 Negatively Regulates B10 Cells Predominantly in an IFNγ Signaling Dependent Manner
por: Chodisetti, Sathi Babu, et al.
Publicado: (2020) -
STAT1 as a central mediator of IFNγ and TLR4 signal integration in vascular dysfunction
por: Sikorski, Krzysztof, et al.
Publicado: (2012)