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mTOR regulates memory CD8 T cell differentiation

Memory CD8 T cells are a critical component of protective immunity and inducing effective memory T cell responses is a major goal of vaccines against chronic infections and tumors 1-3. Considerable effort has gone into designing vaccine regimens that will increase the magnitude of the memory respons...

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Detalles Bibliográficos
Autores principales: Araki, Koichi, Turner, Alexandra P., Shaffer, Virginia Oliva, Gangappa, Shivaprakash, Keller, Susanne A., Bachmann, Martin F., Larsen, Christian P., Ahmed, Rafi
Formato: Texto
Lenguaje:English
Publicado: 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2710807/
https://www.ncbi.nlm.nih.gov/pubmed/19543266
http://dx.doi.org/10.1038/nature08155