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Genome-wide allele- and strand-specific expression profiling
Recent reports have shown that most of the genome is transcribed and that transcription frequently occurs concurrently on both DNA strands. In diploid genomes, the expression level of each allele conditions the degree to which sequence polymorphisms affect the phenotype. It is thus essential to quan...
Autores principales: | Gagneur, Julien, Sinha, Himanshu, Perocchi, Fabiana, Bourgon, Richard, Huber, Wolfgang, Steinmetz, Lars M |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2710863/ https://www.ncbi.nlm.nih.gov/pubmed/19536197 http://dx.doi.org/10.1038/msb.2009.31 |
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