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Comparative systems biology of human and mouse as a tool to guide the modeling of human placental pathology

Placental abnormalities are associated with two of the most common and serious complications of human pregnancy, maternal preeclampsia (PE) and fetal intrauterine growth restriction (IUGR), each disorder affecting ∼5% of all pregnancies. An important question for the use of the mouse as a model for...

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Detalles Bibliográficos
Autores principales: Cox, Brian, Kotlyar, Max, Evangelou, Andreas I, Ignatchenko, Vladimir, Ignatchenko, Alex, Whiteley, Kathie, Jurisica, Igor, Adamson, S Lee, Rossant, Janet, Kislinger, Thomas
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2710868/
https://www.ncbi.nlm.nih.gov/pubmed/19536202
http://dx.doi.org/10.1038/msb.2009.37