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Bioinformatic analysis of xenobiotic reactive metabolite target proteins and their interacting partners
BACKGROUND: Protein covalent binding by reactive metabolites of drugs, chemicals and natural products can lead to acute cytotoxicity. Recent rapid progress in reactive metabolite target protein identification has shown that adduction is surprisingly selective and inspired the hope that analysis of t...
Autores principales: | Fang, Jianwen, Koen, Yakov M, Hanzlik, Robert P |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2711050/ https://www.ncbi.nlm.nih.gov/pubmed/19523227 http://dx.doi.org/10.1186/1472-6769-9-5 |
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