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A Kinetic Model of Trp-Cage Folding from Multiple Biased Molecular Dynamics Simulations
Trp-cage is a designed 20-residue polypeptide that, in spite of its size, shares several features with larger globular proteins. Although the system has been intensively investigated experimentally and theoretically, its folding mechanism is not yet fully understood. Indeed, some experiments suggest...
Autores principales: | Marinelli, Fabrizio, Pietrucci, Fabio, Laio, Alessandro, Piana, Stefano |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2711228/ https://www.ncbi.nlm.nih.gov/pubmed/19662155 http://dx.doi.org/10.1371/journal.pcbi.1000452 |
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