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Mechanism of differential control of NMDA receptor activity by NR2 subunits

NMDA receptors (NMDARs) are a major class of excitatory neurotransmitter receptors in the central nervous system. They form glutamate-gated ion channels highly permeable to calcium that mediate activity-dependent synaptic plasticity1. NMDAR dysfunction is implicated in multiple brain disorders, incl...

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Detalles Bibliográficos
Autores principales: Gielen, Marc, Retchless, Beth Siegler, Mony, Laetitia, Johnson, Jon W., Paoletti, Pierre
Formato: Texto
Lenguaje:English
Publicado: 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2711440/
https://www.ncbi.nlm.nih.gov/pubmed/19404260
http://dx.doi.org/10.1038/nature07993