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Major histocompatibility complex class II-dependent basophil-CD4(+) T cell interactions promote T(H)2 cytokine-dependent immunity

Dendritic cells can prime naïve CD4(+) T cells, however we demonstrate that DC-mediated priming is insufficient for the development of T(H)2 cell-dependent immunity. We identify basophils as a dominant cell population that coexpressed MHC class II and Il4 message following helminth infection. Basoph...

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Detalles Bibliográficos
Autores principales: Perrigoue, Jacqueline G., Saenz, Steven A., Siracusa, Mark C., Allenspach, Eric J., Taylor, Betsy C., Giacomin, Paul R., Nair, Meera G., Du, Yurong, Zaph, Colby, van Rooijen, Nico, Comeau, Michael R., Pearce, Edward J., Laufer, Terri M., Artis, David
Formato: Texto
Lenguaje:English
Publicado: 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2711559/
https://www.ncbi.nlm.nih.gov/pubmed/19465906
http://dx.doi.org/10.1038/ni.1740