The recycling and transcytotic pathways for IgG transport by FcRn are distinct and display an inherent polarity

The Fc receptor FcRn traffics immunoglobulin G (IgG) in both directions across polarized epithelial cells that line mucosal surfaces, contributing to host defense. We show that FcRn traffics IgG from either apical or basolateral membranes into the recycling endosome (RE), after which the actin motor...

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Detalles Bibliográficos
Autores principales: Tzaban, Salit, Massol, Ramiro H., Yen, Elizabeth, Hamman, Wendy, Frank, Scott R., Lapierre, Lynne A., Hansen, Steen H., Goldenring, James R., Blumberg, Richard S., Lencer, Wayne I.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2009
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2711563/
https://www.ncbi.nlm.nih.gov/pubmed/19451275
http://dx.doi.org/10.1083/jcb.200809122

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