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Pro-BDNF–induced synaptic depression and retraction at developing neuromuscular synapses

Postsynaptic cells generate positive and negative signals that retrogradely modulate presynaptic function. At developing neuromuscular synapses, prolonged stimulation of muscle cells induces sustained synaptic depression. We provide evidence that pro–brain-derived neurotrophic factor (BDNF) is a neg...

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Detalles Bibliográficos
Autores principales: Yang, Feng, Je, Hyun-Soo, Ji, Yuanyuan, Nagappan, Guhan, Hempstead, Barbara, Lu, Bai
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2711569/
https://www.ncbi.nlm.nih.gov/pubmed/19451278
http://dx.doi.org/10.1083/jcb.200811147

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