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Decorin is a novel antagonistic ligand of the Met receptor
Decorin, a member of the small leucine-rich proteoglycan gene family, impedes tumor cell growth by down-regulating the epidermal growth factor receptor. Decorin has a complex binding repertoire, thus, we predicted that decorin would modulate the bioactivity of other tyrosine kinase receptors. We dis...
Autores principales: | Goldoni, Silvia, Humphries, Ashley, Nyström, Alexander, Sattar, Sampurna, Owens, Rick T., McQuillan, David J., Ireton, Keith, Iozzo, Renato V. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2711571/ https://www.ncbi.nlm.nih.gov/pubmed/19433454 http://dx.doi.org/10.1083/jcb.200901129 |
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