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VE-PTP controls blood vessel development by balancing Tie-2 activity
Vascular endothelial protein tyrosine phosphatase (VE-PTP) is an endothelial-specific receptor-type tyrosine phosphatase that associates with Tie-2 and VE-cadherin. VE-PTP gene disruption leads to embryonic lethality, vascular remodeling defects, and enlargement of vascular structures in extraembryo...
Autores principales: | Winderlich, Mark, Keller, Linda, Cagna, Giuseppe, Broermann, Andre, Kamenyeva, Olena, Kiefer, Friedemann, Deutsch, Urban, Nottebaum, Astrid F., Vestweber, Dietmar |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2711575/ https://www.ncbi.nlm.nih.gov/pubmed/19451274 http://dx.doi.org/10.1083/jcb.200811159 |
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