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Induction of alternative lengthening of telomeres-associated PML bodies by p53/p21 requires HP1 proteins

Alternative lengthening of telomeres (ALT) is a recombination-mediated process that maintains telomeres in telomerase-negative cancer cells. In asynchronously dividing ALT-positive cell populations, a small fraction of the cells have ALT-associated promyelocytic leukemia nuclear bodies (APBs), which...

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Detalles Bibliográficos
Autores principales:	Jiang, Wei-Qin, Zhong, Ze-Huai, Nguyen, Akira, Henson, Jeremy D., Toouli, Christian D., Braithwaite, Antony W., Reddel, Roger R.
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2009
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2711592/ https://www.ncbi.nlm.nih.gov/pubmed/19468068 http://dx.doi.org/10.1083/jcb.200810084

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