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Rescue of skeletal muscle α-actin–null mice by cardiac (fetal) α-actin
Skeletal muscle α-actin (ACTA1) is the major actin in postnatal skeletal muscle. Mutations of ACTA1 cause mostly fatal congenital myopathies. Cardiac α-actin (ACTC) is the major striated actin in adult heart and fetal skeletal muscle. It is unknown why ACTC and ACTA1 expression switch during develop...
Autores principales: | , , , , , , , , , , , , , , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2711600/ https://www.ncbi.nlm.nih.gov/pubmed/19468071 http://dx.doi.org/10.1083/jcb.200812132 |