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Localization of recombination proteins and Srs2 reveals anti-recombinase function in vivo

Homologous recombination (HR), although an important DNA repair mechanism, is dangerous to the cell if improperly regulated. The Srs2 “anti-recombinase” restricts HR by disassembling the Rad51 nucleoprotein filament, an intermediate preceding the exchange of homologous DNA strands. Here, we cytologi...

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Detalles Bibliográficos
Autores principales:	Burgess, Rebecca C., Lisby, Michael, Altmannova, Veronika, Krejci, Lumir, Sung, Patrick, Rothstein, Rodney
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2009
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2711611/ https://www.ncbi.nlm.nih.gov/pubmed/19506039 http://dx.doi.org/10.1083/jcb.200810055

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